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# Pangenome-guided breeding restores high-altitude adaptation and improves yield in Tartary buckwheat

## Details

**Authors** Zhang et al.

**Year** 2026

**Publisher** Cell

**Discipline** Agriculture & Food

**Secondary disciplines** Genetics

[Read it at the publisher](https://doi.org/10.1016/j.cell.2026.07.035) 
10.1016/j.cell.2026.07.035

## In authors' words

### What they found (results)

A 16-accession Tartary buckwheat pangenome catalogued 123,131 structural variants and found the wild UV-repair gene FtRNH absent from every cultivated variety; restoring it alongside a yield-associated gene (FtPLATZ) improved both stress resilience and yield in high-altitude field trials.

## Commentary

### In short

A gene's presence or absence across cultivars is a hard distinction (D), located within the structural-variant architecture of the whole pangenome (S), and its combination with a second gene produces a causal trait outcome neither gene achieves alone (R).

**Patterns it shows** D, S, R

**Added** 2026-08-17

**How to cite this** Zhang et al. (2026). Pangenome-guided breeding restores high-altitude adaptation and improves yield in Tartary buckwheat. Cell.